mytop is a console-based (non-gui) tool for monitoring the threads and overall performance of a MySQL 3.22.x, 3.23.x, and 4.x server. It runs on most Unix systems (including Mac OS X) which have Perl, DBI, and Term::ReadKey installed. And with Term::ANSIColor installed you even get color. If you install Time::HiRes, you'll get good real-time queries/second stats. As of version 0.7, it even runs on Windows (somewhat).